Edward Mitre Selected Research

Immunoglobulin E (IgE)

1/2020	Chronic infection with a tissue-invasive helminth attenuates sublethal anaphylaxis and reduces granularity and number of mast cells.
1/2020	Axenic Caenorhabditis elegans antigen protects against development of type-1 diabetes in NOD mice.
10/2019	Engineered ovalbumin-expressing regulatory T cells protect against anaphylaxis in ovalbumin-sensitized mice.
10/2015	Ten Weeks of Infection with a Tissue-Invasive Helminth Protects against Local Immune Complex-Mediated Inflammation, but Not Cutaneous Type I Hypersensitivity, in Previously Sensitized Mice.
9/2013	Vaccination with intestinal tract antigens does not induce protective immunity in a permissive model of filariasis.
7/2012	Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization.
11/2011	Anti-FcεR1 antibody injections activate basophils and mast cells and delay Type 1 diabetes onset in NOD mice.
12/2010	Basophils amplify type 2 immune responses, but do not serve a protective role, during chronic infection of mice with the filarial nematode Litomosoides sigmodontis.
4/2006	IgE memory: persistence of antigen-specific IgE responses years after treatment of human filarial infections.
1/2006	Basophils, basophilia and helminth infections.

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Edward Mitre Research Topics

Disease

27	Infections 03/2022 - 02/2004
8	COVID-19 04/2022 - 10/2020
8	Hypersensitivity (Allergy) 01/2020 - 04/2006
5	Filariasis 01/2020 - 04/2006
5	Anaphylaxis (Anaphylactic Shock) 01/2020 - 10/2014
3	Filarial Elephantiasis (Lymphatic Filariasis) 01/2022 - 01/2018
3	Autoimmune Diseases (Autoimmune Disease) 01/2020 - 11/2011
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2020 - 08/2009
3	Inflammation (Inflammations) 01/2018 - 02/2007
2	Parasitic Diseases (Parasitic Disease) 03/2022 - 07/2003
2	Asthma (Bronchial Asthma) 01/2018 - 06/2011
2	Immediate Hypersensitivity 10/2015 - 05/2015
2	Eosinophilia 12/2010 - 01/2006
1	Breakthrough Infections 04/2022
1	Enterobiasis 03/2022
1	Hypothermia 10/2019
1	Allergic Conjunctivitis (Giant Papillary Conjunctivitis) 01/2018
1	Allergic Rhinitis 01/2018
1	Neglected Diseases 01/2017
1	Erythema 10/2014
1	Elephantiasis 08/2013
1	Ocular Onchocerciasis (River Blindness) 08/2013
1	Hepatitis B 06/2011
1	Eczema 06/2011
1	Sepsis (Septicemia) 04/2008
1	Seizures (Absence Seizure) 02/2007
1	Lacunar Stroke 02/2007
1	Vision Disorders (Hemeralopia) 02/2007
1	Hydrocephalus (Hydrocephaly) 02/2007
1	Neurocysticercosis 02/2007

Drug/Important Bio-Agent (IBA)

11	Immunoglobulin E (IgE)IBA 01/2020 - 07/2005
8	AntigensIBA 01/2020 - 02/2004
8	AllergensIBA 10/2019 - 07/2005
7	AntibodiesIBA 04/2022 - 07/2012
6	CytokinesIBA 01/2020 - 01/2006
6	Interleukin-10 (Interleukin 10)IBA 01/2020 - 01/2008
5	Immunoglobulin G (IgG)IBA 11/2020 - 04/2006
5	VaccinesIBA 09/2013 - 04/2006
4	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2019
4	Interleukin-4 (Interleukin 4)IBA 12/2010 - 02/2004
3	AnthelminticsIBA 03/2022 - 06/2011
3	Interleukin-5 (Interleukin 5)IBA 12/2015 - 01/2006
3	Histamine (Histamine Dihydrochloride)FDA Link 01/2015 - 01/2006
2	Mebendazole (Anti-Worm)FDA Link 03/2022 - 12/2020
2	Albendazole (Albenza)FDA Link 03/2022 - 12/2020
2	Messenger RNA (mRNA)IBA 07/2021 - 01/2015
2	COVID-19 VaccinesIBA 07/2021 - 06/2021
2	ovalbumin-alumIBA 01/2020 - 10/2019
2	Interleukin-13IBA 12/2015 - 01/2006
2	InterleukinsIBA 02/2010 - 05/2008
1	Nucleocapsid ProteinsIBA 04/2022
1	SARS-CoV-2 spike proteinIBA 07/2021
1	Glycoproteins (Glycoprotein)IBA 06/2021
1	Praziquantel (Biltricide)FDA Link 12/2020
1	oxfendazoleIBA 01/2020
1	Pharmaceutical PreparationsIBA 01/2020
1	OvalbuminIBA 10/2019
1	Chimeric Antigen ReceptorsIBA 10/2019
1	Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA 01/2019
1	Evans Blue (Blue, Evans)FDA Link 01/2019
1	AcidsIBA 01/2018
1	CollagenIBA 01/2018
1	AS 8IBA 01/2018
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2018
1	Antiparasitic Agents (Antiparasitics)IBA 01/2017
1	Antigen-Antibody Complex (Immune Complex)IBA 10/2015
1	Histidine DecarboxylaseIBA 01/2015
1	aluminum sulfate (alum)IBA 09/2013
1	Tetanus Toxoid (Vaccine, Tetanus)FDA Link 06/2011
1	LipopolysaccharidesIBA 04/2008
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 04/2008
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2008
1	salicylhydroxamic acid (SHAM)IBA 04/2008
1	Prednisone (Sone)FDA LinkGeneric 02/2007
1	Methotrexate (Mexate)FDA LinkGeneric 02/2007
1	Adrenal Cortex Hormones (Corticosteroids)IBA 02/2007
1	Biomarkers (Surrogate Marker)IBA 07/2003

Therapy/Procedure

5	Therapeutics 01/2020 - 02/2007
2	Injections 01/2020 - 11/2011
1	Microspheres (Microsphere) 10/2020
1	Intraperitoneal Injections 01/2020
1	Subcutaneous Injections 01/2018
1	Immunotherapy 05/2015
1	Aftercare (After-Treatment) 04/2006